A novel application of microarray technology, where up to 30,000 whole genomes are printed on a single slide, is described in the journal BMC Microbiology this week. The 'Library on a Slide' will help ...
"The use of genomic microarrays was shown to be useful in the included study population for providing prognostic information regarding time to first treatment. This technique could, with extensive ...
The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...
HOUSTON - Three genomic tests separately predict the likelihood that a patient's breast cancer will reoccur after surgery without additional treatment, and the cancer's vulnerability to chemotherapy ...
Microarrays have been a mainstay of the scientific research community for nearly a decade but given the more stringent demands for accuracy and reliability, have not been as closely embraced in the ...
Gene amplification is one of the major mechanisms of oncogene activation in tumorigenesis. Currently, however, direct identification of amplified genes in cancer remains difficult. The most important ...
Sequencing of the human genome was completed in 2001. Building on the technology and experience of whole-exome sequencing, numerous cancer genomes have been sequenced, including head and neck squamous ...
Impact of BRCA1 gene alterations on tumor characteristics and clinical outcome in ovarian cancer (OC) patients. Background: Advanced ovarian clear cell carcinomas (OCCCs) are notoriously drug ...
The introduction of array comparative genome hybridization (CGH) into prenatal genetic diagnosis presents both challenges and controversy to the clinical cytogenetic community. The challenges are ...
In this post-genomic era, drug discovery and other basic life science research sectors are increasingly utilizing nucleic acid microarrays for comprehensive gene expression studies. Drug discovery ...
A single genetic test could potentially replace the current two-step approach to diagnosing rare developmental disorders in children. This shift could enable earlier diagnoses for families and save ...
NATIONAL HARBOR, Md. -- Genome sequencing of the fetus and both parents in pregnancies with structural anomalies pinpointed a causative genetic variant in nearly a fifth of cases in a prospective ...
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