For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

A new method for visualising chromosomes is painting a truer picture of their shape, which is rarely like the X-shaped blob of DNA most of us are familiar with. Scientists at the BBSRC-funded Babraham ...

Jack has a degree in Medical Genetics from the University of Leicester.View full profile Jack has a degree in Medical Genetics from the University of Leicester. If you think of a chromosome, what ...

A new study challenges prevalent models of chromosome formation during mitotic cell division. The study compared the dimensions of chromosomes in yeasts and humans and found that not only is the width ...

For the first time, researchers see how proteins grab loops of DNA and bundle them for cell division. The discovery also hints at how the genome folds to regulate gene expression. A human cell carries ...

BLOOMINGTON, Ind. -- The structure of how DNA is stored in archaea makes a significant difference to how quickly it evolves, according to a new study by Indiana University researchers. "The most ...

One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we've worked ...

This is a preview. Log in through your library . Abstract Bacterial chromosome (nucleoid) conformation dictates faithful regulation of gene transcription. The conformation is condition-dependent and ...