A) DNA polymerase binds to a single-stranded DNA template (blue) and synthesizes a complementary strand of DNA (red). B) When DNA polymerase randomly incorporates a fluorescently labeled ddNTP base, ...

Commonly used sequencing approaches do not capture full information from both genetics and epigenetics. Some of these may involve separate, parallel workflows and sequencing to produce full ...

A new type of DNA editing enzyme lets scientists directly and permanently change single base pairs of DNA from A*T to G*C. The process could one day enable precise DNA surgery to correct mutations ...

Some people don't want to know the secrets of their DNA, but Dr. Liz Worthey says having it sequenced can help avoid misdiagnoses and harmful drug interactions, among other things. Our team tests, ...

It’s a story UC Santa Cruz Research Professor David Deamer has told many times before: in 1989, while driving along a forested road in Oregon on his way to visit family, an idea struck him. Like many ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

Database searches for DNA sequences that can take biologists and medical researchers days can now be completed in a matter of minutes, thanks to a new search method developed by computer scientists.

The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...